Zygophyllaceae is a family of flowering plants that contains the bean-caper and caltrop. The family includes around 285 species in 22 genera.

Plants in the family Zygophyllaceae may be trees, shrubs, or herbs. They are often found in dry habitats. The leaves are usually opposite, often with stipules and spines. Some are cultivated as ornamental plants, such as Guaiacum, Zygophyllum, Tribulus, and Larrea species. King Clone, a creosote bush (Larrea tridentata) in California, may be the oldest living organism.

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